As I finish writing my Codex Judas Congress paper for the forthcoming volume, I have become interested in ancient depictions of the apostles as the Zodiac signs. The substitution of the patriarchs and also the apostles was not uncommon in ancient Judaism and Christianity. In Christianity, the idea was that once baptized, you were no longer ruled by the old Zodiac signs, but you were reborn and had a new fate controlled by the apostles (=church?). The Zodiac was a powerful image, even found in religious buildings like this sixth century synagogue.
If you know of any ancient art depicting especially the disciples substituting for the Zodiac signs, please share this in the comments, and I'll try to post this information.
6th c., Zodiac on synagogue floor of Beit Alpha, Beit She'an Valley.